Adaptive Circuit Targeting (ACT) DBS combines the “when to stimulate” approach of adaptive DBS with the “where to stimulate” principle of connectomic DBS. By decoding symptoms in real time and targeting the right brain circuits, it promises more personalized and effective treatment for conditions like Parkinson’s, dystonia, and OCD. While challenges remain—such as improved sensing, circuit mapping, and smarter hardware—the technology is advancing quickly toward truly intellig